Found 147 articles for: "actinic keratosis"
Photodynamic Therapy Effectively Treats Actinic Keratoses Without Pre-Illumination Incubation Time
March 2017 | Volume 16 | Issue 3 | Case Reports | 275 | Copyright © March 2017
BACKGROUND: Actinic keratoses (AKs) are dysplastic lesions of the epidermis that have the potential to progress to non-melanoma skin cancers (NMSC). Traditional photodynamic therapy (PDT) requires ...
Read MoreSubungual Melanoma In Situ Treated With Imiquimod 5% Cream After Conservative Surgery Recurrence
March 2017 | Volume 16 | Issue 3 | Case Reports | 268 | Copyright © March 2017
Subungual melanoma is a rare variant of acral lentiginous melanoma that often has a poor prognosis compared with other types of melanoma. The aim of the present study is to report a case of a patie...
Read MoreExpert Consensus on Cosmetic Outcomes After Treatment of Actinic Keratosis
March 2017 | Volume 16 | Issue 3 | Original Article | 260 | Copyright © March 2017
Dermatologists treat actinic keratosis (AK) primarily because these lesions have the potential to progress to invasive squamous cell carcinoma. Patients, on the other hand, generally seek treatment...
Read MoreCLINICAL TRIAL REVIEW
February 2017 | Volume 16 | Issue 2 | Features | 183 | Copyright © February 2017
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs and devices undergoing clinical testing. It is our goal to inform the reader of the status of select...
Read MoreRegression Analysis of Local Skin Reactions to Predict Clearance of Actinic Keratosis on the Face in Patients Treated With Ingenol Mebutate Gel: Experience from Randomized Controlled Trials
February 2017 | Volume 16 | Issue 2 | Original Article | 112 | Copyright © February 2017
Ingenol mebutate gel, a topical field treatment for actinic keratosis (AK), elicits inflammatory application-site reactions in most patients. This analysis explored the relationship between the int...
Read MoreThe Photodynamic Therapy Experience of a High Volume Laser and Dermatologic Surgery Center
November 2016 | Volume 15 | Issue 11 | Original Article | 1420 | Copyright © November 2016
BACKGROUND: Photodynamic therapy (PDT) is an FDA approved treatment for actinic keratoses (AK’s) although multiple off-label indi- cations are reported. Despite frequent use for AK’s, no clear con...
Read MoreTreatment of Facial Photodamage With Mass Market Topical Products vs Non-ablative Fractional Laser
November 2016 | Volume 15 | Issue 11 | Original Article | 1366 | Copyright © November 2016
METHODS: In this split-face, evaluator-blinded study, 18 subjects were randomly assigned to receive either the SSR or NFL treatments on each side of the face. For the SSR facial sides subjects followe...
Read MoreDaylight-Photodynamic Therapy for the Treatment of Actinic Keratosis in Different Seasons
November 2015 | Volume 14 | Issue 11 | Original Article | 1349 | Copyright © November 2015
BACKGROUND: non-melanoma skin cancer (NMSC) is the most common malignancy, whose public health significance is often unrecognized. Its incidence continues to grow at an alarming rate, becoming an occu...
Read MoreNew Methods for the Clinical Enhancement of Photodynamic Therapy
November 2015 | Volume 14 | Issue 11 | Original Article | 1329 | Copyright © November 2015
The prolonged incubation time of Photodynamic Therapy (PDT) as well as the need for two treatments to achieve high efficacy have motivated physicians to experiment with treatment parameters and PDT en...
Read MoreEvaluation of a Low Energy, Low Density, Non-Ablative Fractional 1927nm Wavelength Laser for Facial Skin Resurfacing
November 2015 | Volume 14 | Issue 11 | Original Article | 1262 | Copyright © November 2015
OBJECTIVE: We investigated the safety, tolerability and efficacy of a low energy low density, non-ablative fractional 1,927-nm laser in the treatment of facial photodamage, melasma, and post inflammat...
Read MoreA Controlled Comparison Study of Topical Fluourouracil 5% Cream Pre-Treatment of Aminolevulinic Acid/Photodynamic Therapy for Actinic Keratosis
November 2015 | Volume 14 | Issue 11 | Original Article | 1241 | Copyright © November 2015
INTRODUCTION: Topical Fluorouracil 5% cream (5-FU) and 20% aminolevulinic acid (ALA)/ photodynamic therapy (PDT) are both FDA approved for the treatment of Actinic Keratosis (AK). We have studied the ...
Read MoreLaser and Light-Based Aesthetics in Men
September 2015 | Volume 14 | Issue 9 | Original Article | 1061 | Copyright © September 2015
Men represent an important evolving segment of the cosmetic market. With the growing acceptability of cosmetic procedures along with societal and workplace pressure to maintain youthfulness, men incre...
Read MoreComparative Effects of Sunscreens Alone vs Sunscreens Plus DNA Repair Enzymes in Patients With Actinic Keratosis: Clinical and Molecular Findings from a 6-Month, Randomized, Clinical Study
September 2015 | Volume 14 | Issue 9 | Original Article | 986 | Copyright © September 2015
Recent experimental irradiation studies have shown that the addition of DNA repair enzymes (photolyase and endonuclease) to traditional sunscreens may reduce ultraviolet radiation (UVR)-induced molecu...
Read MoreEffect of Field Treatment of Actinic Keratosis With Ingenol Mebutate Gel on the Identification of Lesions for Biopsy
August 2015 | Volume 14 | Issue 8 | Original Article | 813 | Copyright © August 2015
Actinic keratoses (AKs) are premalignant skin lesions caused by cumulative ultraviolet-light exposure that may progress to invasive squamous cell carcinoma (SCC). As the clinical presentation of AKs v...
Read MoreCryo-Induced Thermal Wounds: A Human Acute Wound Model
July 2015 | Volume 14 | Issue 7 | Original Article | 734 | Copyright © July 2015
INTRODUCTION: Clinical models are invaluable in studying wound healing. Challenges in studying human wounds include heterogeneity of patients and wounds, as well as prolonged study time, resulting in ...
Read MoreFive-Year Trend in the Number of Dermatologic Clinical Drug Trials Registered on ClinicalTrials.gov
May 2015 | Volume 14 | Issue 5 | Original Article | 497 | Copyright © May 2015
BACKGROUND: There is a reported global decrease in the number of clinical trials conducted in recent years. We aimed to determine if this declining trend can be extrapolated to dermatologic clinical t...
Read MoreBefore OR After: Is There a Connection Between the Use of Adjunctive Nonmelanoma Skin Cancer Treatments and Subsequent Invasive Tumors?
May 2015 | Volume 14 | Issue 5 | Editorials | 450 | Copyright © May 2015
Although the therapeutic gold standard for basal cell carcinomas (BCCs) is surgical excision, imiquimod, fluorouracil cream, and photodynamic therapy are frequently used. All 3 modalities have been sh...
Read MoreDNA Repair Enzymes: An Important Role in Skin Cancer Prevention and Reversal of Photodamage‑ A Review of the Literature
March 2015 | Volume 14 | Issue 3 | Original Article | 297 | Copyright © March 2015
The incidence of skin cancer continues to increase annually despite preventative measures. Non-melanoma skin cancer affects more than 1,000,000 people in the United States every year.1 The ...
Read MorePrinciples and Approaches for Optimizing Therapy With Unique Topical Vehicles
December 2014 | Volume 13 | Issue 12 | Features | 1431 | Copyright © December 2014
Nonsurgical Treatment Options for Basal Cell Carcinoma - Focus on Advanced Disease
December 2013 | Volume 12 | Issue 12 | Original Article | 1369 | Copyright © December 2013
Basal cell carcinoma (BCC) is the most common cancer in the world. It is typically slow growing and usually effectively managed with surgery. However, BCCs in some patients are unsuitable for surgery...
Read More